Clinical Features and Visual Outcome of Uveitis in Japanese Patients Younger than 18 Years
Clinical Features and Visual Outcome of Uveitis in Japanese Patients Younger than 18 Years
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日本 18 岁以下患者葡萄膜炎的临床特征和视力结果
DOI：
10.1080/09273948.2020.1726972
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发表时间：
2020
影响因子：
3.3
通讯作者：
Aihara Makoto
中科院分区：
文献类型：
--
作者：
Kitano Marie;Tanaka Rie;Kaburaki Toshikatsu;Nakahara Hisae;Shirahama Shintaro;Suzuki Takafumi;Komae Keiko;Aihara Makoto
目的：研究日本年轻葡萄膜炎患者的临床特征和视力结果。方法：对2000年至2018年期间在东京大学医院就诊的18岁以下葡萄膜炎患者进行回顾性分析。结果：该研究包括98例患者，平均年龄为12.3 ± 3.8岁。前葡萄膜炎占52.0%，全葡萄膜炎占37.8%，后葡萄膜炎占10.2%。最常见的诊断是青少年慢性虹膜睫状体炎（JCI）（29.6%），其次是肾小管间质性肾炎和葡萄膜炎综合征（4.1%）和神经视网膜炎（4.1%）。39例患者接受全身抗炎治疗。在所有受试者中，56%出现眼部并发症，20%接受眼部手术。6.2%的患者视力为20/200或更低。视力下降的常见原因是低眼压、浆液性视网膜脱离和瞳孔异常。低眼压、浆液性视网膜脱离和瞳孔障碍可导致视力丧失。
Purpose: To investigate the clinical features and visual outcome of young Japanese patients with uveitis.Methods: Patients younger than 18 years who presented with uveitis at the University of Tokyo Hospital between 2000 and 2018 were retrospectively reviewed.Results: The study comprised 98 patients whose mean age was 12.3 ± 3.8 years. Anterior uveitis was present in 52.0%, panuveitis in 37.8%, and posterior uveitis in 10.2%. The most common diagnosis was juvenile chronic iridocyclitis (JCI) (29.6%) followed by tubulointerstitial nephritis and uveitis syndrome (4.1%) and neuroretinitis (4.1%). Thirty-nine patients received systemic anti-inflammatory treatment. Among all subjects, 56% presented with ocular complications and 20% underwent ocular surgery. Visual acuity of 20/200 or less was observed in 6.2%. The common causes of decreased vision were hypotony, serous retinal detachment, and pupil disorder.Conclusions: JCI was the most common diagnosis. Hypotony, serous retinal detachment, and pupil disorder can lead to visual loss.