Epidemiology of polyps in the rectum and sigmoid colon. Evaluation of nutritional factors.
Epidemiology of polyps in the rectum and sigmoid colon. Evaluation of nutritional factors.
复制标题
直肠和乙状结肠息肉的流行病学。
DOI：
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发表时间：
1986
影响因子：
1.9
通讯作者：
S. Larsen
中科院分区：
文献类型：
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作者：
G. Hoff;I. E. Moen;K. Trygg;W. Frölich;J. Sauar;M. Vatn;E. Gjone;S. Larsen
流行病学研究表明饮食与结直肠癌之间存在关联。然而，病例/对照研究很少，基于对有癌症症状的癌症患者进行访谈的研究不可避免地容易产生偏见。一项用于检测结直肠腺瘤的内窥镜人群筛查研究在连续5个工作日期间进行了饮食双盲登记。参与者和营养师都没有被告知内窥镜检查的结果。23种营养成分的估计是根据对当地商业食品和挪威食品成分的分析得出的。结果表明，在肿瘤变化增加的情况下，脂肪的消耗量增加，纤维和十字花科蔬菜的消耗量减少。目前的材料将构成饮食相关的后续研究的基础。
Epidemiological studies have suggested an association between diet and colorectal cancer. Case/control studies, however, have been scarce, and studies based on interview with cancer patients who have symptoms from their cancer are inevitably prone to bias. An endoscopic population screening study for detection of colorectal adenomas enabled a double-blind registration of diet during 5 consecutive weekdays. Neither the participant nor the dietitian was informed of the findings at endoscopy. The estimation of 23 nutritional components was based on analysis of local commercial food and on the composition of foods in Norway. Results showed increasing consumption of fat and decreasing consumption of fiber and cruciferous vegetables in the presence of increasing neoplastic changes. The present material will form the basis for dietary-related follow-up studies.