Surface plasmon sensor based on the enhanced light transmission through arrays of nanoholes in gold films
Surface plasmon sensor based on the enhanced light transmission through arrays of nanoholes in gold films
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DOI：
10.1021/la0493621
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发表时间：
2004-06-08
期刊：
影响因子：
3.9
通讯作者：
Kavanagh, KL
中科院分区：
文献类型：
--
作者：
Brolo, AG;Gordon, R;Kavanagh, KL
金膜中的纳米孔阵列用于监测有机和生物分子与金属表面的结合。这种技术对表面结合事件特别敏感，因为它是基于通过纳米孔阵列的共振表面等离子体增强传输。的灵敏度被认为是400纳米每折射率单位，这是可比的其他光栅为基础的表面等离子体共振（SPR）设备。纳米孔阵列非常适合于传感器芯片中的密集集成。此外，光学几何形状是共线的，这相对于用于SPR感测的传统Kretschmann（反射）布置简化了对准。
Arrays of nanoholes in a gold film were used to monitor the binding of organic and biological molecules to the metallic surface. This technique is particularly sensitive to surface binding events because it is based upon the resonant surface plasmon enhanced transmission through the array of nanoholes. The sensitivity was found to be 400 nm per refractive index unit, which is comparable to other grating-based surface plasmon resonance (SPR) devices. The array of nanoholes is well suited for dense integration in a sensor chip. Furthermore, the optical geometry is collinear, which simplifies the alignment with respect to the traditional Kretschmann (reflection) arrangement for SPR sensing.