The panorama of cerebral palsy in Sweden. XI. Changing patterns in the birth-year period 2003-2006
The panorama of cerebral palsy in Sweden. XI. Changing patterns in the birth-year period 2003-2006
复制标题
DOI：
10.1111/apa.12614
复制
发表时间：
2014-06-01
期刊：
影响因子：
3.8
通讯作者：
Uvebrant, Paul
中科院分区：
文献类型：
--
作者：
Himmelmann, Kate;Uvebrant, Paul
目的描述瑞典西部地区脑性瘫痪(CP)的流行情况。方法对2003年至2006年该地区94466例活产儿进行人群调查。记录出生特征和神经影像表现，计算患病率，分析病因。结果206例儿童中发现CP，包括新生儿后病例，粗略发病率为2.18/1000活产儿。36周的胎龄别患病率。偏瘫占44%，双瘫占29%，四肢瘫痪占6%，运动障碍占16%，共济失调占5%。95%的儿童接受了神经成像检查。表现为发育不良占13%，白质损害占36%，皮质/皮质下损害占23%，基底节损害占14%。36%的病因为产前病因，46%为围产期/新生儿病因，18%未分类。结论瑞典西部地区CP患病率总体稳定。然而，脑瘫类型的分布发生了变化，偏瘫的术语显著增加。在极早产的脑性瘫痪儿童中，26周前出生的比例有所增加。
AimTo describe the epidemiology of cerebral palsy (CP) in western Sweden.MethodsA population-based study covering 94466 live births in the area in 2003-2006. Birth characteristics and neuroimaging findings were recorded, prevalence was calculated and aetiology was analysed.ResultsCP was found in 206 children, including postneonatal cases, corresponding to a crude prevalence of 2.18 per 1000 live births. The gestational age-specific prevalence for 36weeks. Hemiplegia accounted for 44%, diplegia for 29% and tetraplegia for 6%, while 16% had dyskinetic CP and 5% had ataxia. Neuroimaging was available in 95% of the children. This showed maldevelopment in 13%, white matter lesions in 36%, cortical/subcortical lesions in 23% and basal ganglia lesions in 14%. The aetiology was considered to be prenatal in 36% and perinatal/neonatal in 46% and remained unclassified in 18%.ConclusionThe overall prevalence of CP in western Sweden was stable. However, the distribution of CP types changed and the term hemiplegia increased significantly. Among children with CP born extremely preterm, the percentage born before 26weeks of gestation had increased.