THE CHEMISTRY OF THE TRITERPENES AND RELATED COMPOUNDS .18. ELUCIDATION OF THE STRUCTURE OF POLYPORENIC ACID-C
THE CHEMISTRY OF THE TRITERPENES AND RELATED COMPOUNDS .18. ELUCIDATION OF THE STRUCTURE OF POLYPORENIC ACID-C
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DOI：
10.1039/jr9530002548
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发表时间：
1953-01-01
期刊：
影响因子：
--
通讯作者：
LEMIN, AJ
中科院分区：
文献类型：
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作者：
BOWERS, A;HALSALL, TG;LEMIN, AJ
聚聚二烯酸C被表征为一种三萜类四环羟基酮羧酸，其分子式为C，， Hd604。它的结构（XXXIV）最终通过转化为乙二酸的衍生物而建立，乙二酸又被转化为羊毛甾醇衍生物（Holker, Powell, Robertson, Simes, Wright, and Gascoigne， J., 1953,2422）。绿灰酸和聚聚二烯酸C可以看作是三甲基麦角甾的衍生物。特别有趣的是，侧链的碳骨架与主要真菌甾醇麦角甾醇的碳骨架相同，这表明它们在生物合成中有一些共同的途径。
Polyporenic acid C has been characterised as a triethenoid tetracyclic hydroxy-keto-carboxylic acid with the formula C,, Hd604. Its structure (XXXIV) has been finally established by conversion into a derivative of eburicoic acid which has in turn been converted (Holker, Powell, Robertson, Simes, Wright, and Gascoigne, J., 1953, 2422) into a lanosterol derivative. Eburicoic acid and polyporenic acid C can be regarded as derivatives of trimethylergostane. It is of particular interest that the carbon skeleton of the side chains is identical with that of the major fungal sterol, ergosterol, suggesting some common paths in their biosynthesis.