Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography - A comparison with magnetic resonance imaging
Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography - A comparison with magnetic resonance imaging
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DOI：
10.1016/j.jacc.2004.05.068
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发表时间：
2004-09-01
影响因子：
24
通讯作者：
Skjaerpe, T
中科院分区：
文献类型：
--
作者：
Malm, S;Frigstad, S;Skjaerpe, T
我们评估了对比超声心动图与组织谐波成像测量左心室（LV）容积和射血分数（EF）的准确性和可重复性相比，磁共振成像（MRI）。方法收集了110例连续患者的心尖左心室视图的数字回波记录前后静脉造影剂。使用1.5 T扫描仪对多个左心室短轴切片进行磁共振成像。用圆盘法离线计算左心室容积和EF。30例随机选择的患者进行再分析观察者内和观察者间的variability.Results与基线相比，对比回波增加了单平面和双平面体积分析的可行性从87%到100%和从79%到95%，分别。Bland-Altman分析证实了超声心动图的体积低估，但对比度不太明显。超声心动图和MRI之间的一致性界限随着造影剂的使用而显著缩小：从-18.1%至8.3%至-7.7%至4.1%（EF），从-98.2至-11.7 ml至-59.0至10.7 ml（舒张末期容积），从-58.8至21.8 ml至-38.6至23.9 ml（收缩末期容积）。23例患者造影前超声和MRI的射血分数差异大于或等于10%（EF单位），对比造影后为0（p < 0.001）。在intraobserver和interobserver分析，EF的协议范围缩小显着contrast.CONCLUSIONS在非选定的心脏病患者的LV容量和EF的二维超声心动图评价被认为是更准确和可重复的，当添加静脉造影剂。(C)2004年，美国心脏病学会基金会。
OBJECTIVES We evaluated the accuracy and reproducibility of contrast echocardiography versus tissue harmonic imaging for measurements of left ventricular (LV) volumes and ejection fraction (EF) compared to magnetic resonance imaging (MRI).METHODS Digital echo recordings of apical LV views before and after intravenous contrast were collected from 110 consecutive patients. Magnetic resonance imaging of multiple short-axis LV sections was performed with a 1.5-T scanner. Left ventricular volumes and EF were calculated offline by method of discs. Thirty randomly selected patients were reanalyzed for intraobserver and interobserver variability.RESULTS Compared with baseline, contrast echo increased feasibility for single-plane and biplane volume analysis from 87% to 100% and from 79% to 95%, respectively. The Bland-Altman analysis demonstrated volume underestimation by echo, but much less pronounced with contrast. Limits of agreement between echo and MRI narrowed significantly with contrast: from -18.1% to 8.3% to -7.7% to 4.1% (EF), from -98.2 to -11.7 ml to -59.0 to 10.7 ml (end-diastolic volume), and from -58.8 to 21.8 ml to -38.6 to 23.9 ml (end-systolic volume). Ejection fraction from precontrast echo and MRI diffiered by greater than or equal to10% (EF units) in 23 patients versus 0 after contrast (p < 0.001). At intraobserver and interobscrver analysis, limits of agreement for EF narrowed significantly with contrast.CONCLUSIONS The two-dimensional echocardiographic evaluation of LV volumes and EF in non-selected cardiac patients was found to be more accurate and reproducible when adding an intravenous contrast agent. (C) 2004 by the American College of Cardiology Foundation.