Radiation effect on the proliferating capillaries in rat transparent chambers.
Radiation effect on the proliferating capillaries in rat transparent chambers.
复制标题
辐射对大鼠透明室中增殖的毛细血管的影响。
DOI：
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发表时间：
1976
期刊：
影响因子：
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通讯作者：
Taiju Matsuzawa
中科院分区：
文献类型：
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作者：
H. Yamaura;Kenji Yamada;Taiju Matsuzawa
通过血管分布的变化定量研究增殖血管对大鼠透明腔断流区域的血运重建。在血管化边界上，形成约0-5mm宽的富血管区。边界每天以0-020厘米的速度不断前进。修复区域的血管密度是固定的。血管长度和修复面积呈抛物线增加。用 50、100、200、400、1000、2000 和 4000 拉德的 30Co 伽马射线单剂量照射这些室，并检查对边界前进的影响。在 200 rad 或更高的强度下，在边界的前进中观察到显着的抑制，剂量越大，抑制越明显。边界的退化也发生了。超过 1000 拉德的辐射破坏了富血管区。
The revascularization of the devascularized area in rat transparent chambers by the proliferating blood vessels was studied quantitatively on the changes of vascularity. On the vascularizing border, a hypervascular zone about 0-5 mm wide was formed. The border advanced constantly at 0-020 cm a day. Vascular density was fixed in the repaired area. The vascular length and repaired area increased on parabolic curves. The chambers were irradiated with single doses of 50, 100, 200, 400, 1000, 2000, and 4000 rad of 30Co gamma-rays, and the effects on the advance of the border were examined. With 200 rad and more, significant inhibition, greater with bigger doses, was seen in the advance of the borders. Regression of the borders also occurred. Irradiation with over 1000 rad destroyed the hypervascular zones.