Connectivity-based segregation of the human striatum predicts personality characteristics
Connectivity-based segregation of the human striatum predicts personality characteristics
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DOI：
10.1038/nn.2228
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发表时间：
2009-01-01
影响因子：
25
通讯作者：
Weber, Bernd
中科院分区：
文献类型：
--
作者：
Cohen, Michael X.;Schoene-Bake, Jan-Christoph;Weber, Bernd
我们发现人格特征与人脑内可分离的连接通路相关。包括海马体和杏仁核在内的皮质下网络与腹侧纹状体之间的纤维束可预测新奇寻求方面的个体差异，而前额叶皮质与纹状体之间的纤维束可预测奖赏依赖方面的个体差异。这些发现表明，边缘 - 纹状体连接的强度可能在一定程度上是人类人格特质的基础。
We found that personality characteristics are linked to dissociable connectivity streams in the human brain. Whereas fiber tracts between a subcortical network, including the hippocampus and amygdala, and the ventral striatum predicted individual differences in novelty seeking, tracts between prefrontal cortex and the striatum predicted individual differences in reward dependence. These findings suggest that the strength of limbic-striatal connectivity may, in part, underlie human personality traits.