Investigation on the nasal airflow characteristics of anterior nasal cavity stenosis.
Investigation on the nasal airflow characteristics of anterior nasal cavity stenosis.
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DOI：
10.1590/1414-431x20165182
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发表时间：
2016-08-01
期刊：
影响因子：
--
通讯作者：
Deng J
中科院分区：
文献类型：
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作者：
Wang T;Chen D;Wang PH;Chen J;Deng J
我们使用计算流体动力学（CFD）模型，通过比较手术前和手术后的气流特征，来研究鼻腔前腔狭窄患者的吸气气流分布。20例严重前鼻腔狭窄患者（包括1例双侧狭窄）接受了计算机断层扫描（CT）进行CFD建模。模拟并分析了手术前后鼻腔气流特性。20例患者鼻腔最窄区域均位于鼻阀区域内，平均截面积由术前0.39 cm2增加至术后0.78 cm2 （P<0.01）。鼻阀区平均气流速度由6.19 m/s降至2.88 m/s （P<0.01）。手术恢复双侧鼻腔的鼻对称，使窄侧鼻阻力从0.24 Pa降低。s/mL至0.11 Pa。s /毫升(P < 0.01)。对前鼻腔狭窄患者的鼻腔进行数值模拟，揭示了鼻腔结构的变化及其导致的鼻腔气流模式。手术实现了平衡的双侧鼻腔通气和减少鼻腔狭窄区域的鼻阻力。鼻瓣膜狭窄的矫正是减少鼻阻力必不可少的，也是获得满意疗效的关键。
We used a computational fluid dynamics (CFD) model to study the inspiratory airflow profiles of patients with anterior nasal cavity stenosis who underwent curative surgery, by comparing pre- and postoperative airflow characteristics. Twenty patients with severe anterior nasal cavity stenosis, including one case of bilateral stenosis, underwent computed tomography (CT) scans for CFD modelling. The pre- and postoperative airflow characteristics of the nasal cavity were simulated and analyzed. The narrowest area of the nasal cavity in all 20 patients was located within the nasal valve area, and the mean cross-sectional area increased from 0.39 cm2 preoperative to 0.78 cm2 postoperative (P<0.01). Meanwhile, the mean airflow velocity in the nasal valve area decreased from 6.19 m/s to 2.88 m/s (P<0.01). Surgical restoration of the nasal symmetry in the bilateral nasal cavity reduced nasal resistance in the narrow sides from 0.24 Pa.s/mL to 0.11 Pa.s/mL (P<0.01). Numerical simulation of the nasal cavity in patients with anterior nasal cavity stenosis revealed structural changes and the resultant patterns of nasal airflow. Surgery achieved balanced bilateral nasal ventilation and decreased nasal resistance in the narrow region of the nasal cavity. The correction of nasal valve stenosis is not only indispensable for reducing nasal resistance, but also the key to obtain satisfactory curative effect.