Proneness to psychological distress and risk of Alzheimer disease in a biracial community
Proneness to psychological distress and risk of Alzheimer disease in a biracial community
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DOI：
10.1212/01.wnl.0000149525.53525.e7
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发表时间：
2005-01-25
期刊：
影响因子：
9.9
通讯作者：
Evans, DA
中科院分区：
文献类型：
--
作者：
Wilson, RS;Barnes, LL;Evans, DA
居住在混血儿社区的非痴呆症患者完成了一份简明的心理压力倾向性量表，随后在3至6年后对1064人进行了阿尔茨海默病(AD)事件的检查。在对选定的人口统计学和临床变量进行控制的分析中，易患抑郁症的人患AD的可能性是不易患抑郁症的人的2.4倍。与非裔美国人相比，白人的这种影响要强得多。
Persons without dementia residing in a biracial community completed a brief scale of proneness to psychological distress, and 1,064 were subsequently examined for incident Alzheimer disease ( AD) 3 to 6 years later. In analyses controlling for selected demographic and clinical variables, persons prone to distress were 2.4 times more likely to develop AD than persons not distress prone. This effect was substantially stronger in white persons compared to African Americans.