SimiTri - visualizing similarity relationships for groups of sequences
SimiTri - visualizing similarity relationships for groups of sequences
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DOI：
10.1093/bioinformatics/btf870
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发表时间：
2003-02-12
期刊：
影响因子：
5.8
通讯作者：
Blaxter, M
中科院分区：
文献类型：
--
作者：
Parkinson, J;Blaxter, M
大型数据集之间的全局序列比较，例如来自基因组计划的数据集，在显示和分析方面可能存在问题。我们已经开发了SimiTiri，一个基于Java/Perl的应用程序，它允许同时显示和分析三个不同数据库的数据集的相对相似性关系。我们说明了它的效用，在确定秀丽隐杆线虫基因，具有不同的模式的系统发育亲和力暗示水平基因转移。SimiTri可从http://www.nematodes.org/SimiTri/免费下载，源代码可从作者处免费获得。
Global sequence comparisons between large datasets, such as those arising from genome projects, can be problematic to display and analyze. We have developed SimiTiri, a Java/Perl-based application, which allows simultaneous display and analysis of relative similarity relationships of the dataset of interest to three different databases. We illustrate its utility in identifying Caenorhabditis elegans genes that have distinct patterns of phylogenetic affinity suggestive of horizontal gene transfer. SimiTri is freely downloadable from http://www.nematodes.org/SimiTri/ and the source code is freely available from the authors.