Explosive outbursts in children with Tourette's disorder
Explosive outbursts in children with Tourette's disorder
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DOI：
10.1097/00004583-200010000-00014
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发表时间：
2000-10-01
影响因子：
13.3
通讯作者：
Olson, M
中科院分区：
文献类型：
--
作者：
Budman, CL;Bruun, RD;Olson, M
目的：抽动秽语障碍（Tourette 'sdisorder，TD）患儿常发生突发性、爆发性行为.这些症状的病因尚不清楚。本研究探讨爆发性精神障碍与其共病的关系。方法：抽动类型和严重程度，并存在特定的共病障碍进行了比较，在37例儿童TD和爆炸性爆发和31例儿童TD谁没有这样的症状。结果如下：TD和爆发性发作的儿童更可能表现出显著的共病状况，特别是注意力缺陷/多动障碍、强迫症和对立违抗性障碍。抽搐的类型和严重程度似乎与爆炸性爆发的存在无关。一个高度显着的关系被证明之间的数量共病精神病诊断和爆炸性爆发。结论：TD儿童的爆发性发作类似于间歇性爆发性障碍，可能反映了大脑功能不同领域的失调。这些症状的出现应该提醒临床医生潜在的共病情况。
Objective: Sudden, explosive outbursts of behavior occur in some children with Tourette's disorder (TD). The etiology of these symptoms is unknown. This study investigated the relationship between explosive outbursts, TD, and its comorbid disorders. Method: Tic type and severity and the presence of specific comorbid disorders were compared in 37 children with TD and explosive outbursts and 31 children with TD who did not have such symptoms. Results: Children with TD and explosive outbursts were more likely to demonstrate significant comorbid conditions, particularly attention-deficit/hyperactivity disorder, obsessive-compulsive disorder, and oppositional defiant disorder. Tic type and severity did not appear related to the presence of explosive outbursts. A highly significant relationship was demonstrated between the number of comorbid psychiatric diagnoses and explosive outbursts. Conclusions: Explosive outbursts in children with TD resemble intermittent explosive disorder and may reflect dysregulation of diverse domains of brain function. The presence of such symptoms should alert the clinician to underlying comorbid conditions.