Insect allatotropins belong to a family of structurally-related myoactive peptides present in several invertebrate phyla
Insect allatotropins belong to a family of structurally-related myoactive peptides present in several invertebrate phyla
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DOI：
10.1016/j.peptides.2003.08.011
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发表时间：
2003-10-01
期刊：
影响因子：
3
通讯作者：
Horodyski, FM
中科院分区：
文献类型：
--
作者：
Elekonich, MM;Horodyski, FM
最初因其刺激鳞翅目昆虫产生保幼激素的能力而得名，现已成为一种具有多种神经、内分泌和肌肉活动作用的神经肽。本文描述了促生长素作用的实验证据，它在几种昆虫中的定位，以及它对各种不同组织的多重作用，导致血淋巴循环和肠道运动的增加。总体的生理效应还可能包括物种特有的效应，如调节养分吸收、调节昼夜节律和准备迁徙。此外，我们提出的证据表明，促生长激素是在几个无脊椎动物门中发现的肌动活性多肽家族的成员。最后，我们推测促生长素的肌动特性是基础的，可能是促幼激素合成的刺激作用是二次进化的。(C)2003 Elsevier Inc.保留所有权利。
Originally named for its ability to stimulate juvenile hormone production by lepidopteran corpora allata, allatotropin has emerged as a neuropeptide with multiple neural, endocrine and myoactive roles. This paper describes the experimental evidence for allatotropin action, its localization in several species of insects, and its multiple effects on a variety of different tissues that lead to increased hemolymph circulation and gut motility. The overall physiological effects may also include species-specific effects such as the regulation of nutrient absorption, modulation of the circadian cycle and migratory preparedness. In addition, we present evidence suggesting that allatotropins are members of a family of myoactive peptides found in several invertebrate phyla. Finally, we speculate that the myoactive properties of allatotropins are basal and it is likely that the stimulatory action of allatotropins on juvenile hormone synthesis evolved secondarily. (C) 2003 Elsevier Inc. All rights reserved.