EVALUATION OF THE VISUAL-SYSTEM IN MULTIPLE-SCLEROSIS - A COMPARATIVE-STUDY OF DIAGNOSTIC-TESTS
EVALUATION OF THE VISUAL-SYSTEM IN MULTIPLE-SCLEROSIS - A COMPARATIVE-STUDY OF DIAGNOSTIC-TESTS
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DOI：
10.1016/0303-8467(92)90088-k
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发表时间：
1992-09-01
影响因子：
1.9
通讯作者：
POLMAN, CH
中科院分区：
文献类型：
--
作者：
VANDIEMEN, HAM;LANTING, P;POLMAN, CH
对22例临床确诊的多发性硬化(MS)患者进行视觉诱发电位(VEP)、对比敏感度试验(CS)、脱色试验(FOC)、石原色觉试验(CV)和瞳孔光反射(PLR)检查。VEP异常率81.8%，CS异常率72.7%，FOC异常率36.4%，CV异常率31.8%，PLR异常率52.3%。VEP和CS联合应用最为敏感，90.9%(20/22)的无症状患者可检出视觉系统亚临床损害。
In 22 patients with clinically definite multiple sclerosis (MS) who were without visual symptoms and had a visual acuity of at least 1.0 in both eyes at the time of measurement, the following tests were performed to detect subclinical lesions in the visual system: visual evoked potential (VEP), contrast sensitivity test (CS), flight of colours test (FOC), colour vision test (Ishihara plates) (CV) and the pupillary light reflex (PLR). VEP was abnormal in 81.8%, CS in 72.7%, FOC in 36.4%, CV in 31.8%, and PLR in 52.3% of the patients. VEP and CS together were most sensitive: combining these techniques subclinical lesions of the visual system were detected in 90.9% (20/22) of these asymptomatic patients.