Eph receptors and ephrins engage in cellular cannibalism.
Eph receptors and ephrins engage in cellular cannibalism.
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Eph 受体和肝配蛋白参与细胞自相残杀。
DOI:
10.1083/jcb.201908074
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Pasquale,ElenaB
中科院分区:
文献类型:
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作者:
Pasquale,ElenaB
Eph receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signaling molecules. Execution of their signature repulsive program then generates pulling forces, enabling a cell to engulf a piece of another cell. New mechanistic insights by Gong et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201901032) define this process as a form of “cellular cannibalism.”