Validation of a hepatitis C screening tool in primary care
Validation of a hepatitis C screening tool in primary care
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DOI：
10.1001/archinte.168.18.2009
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发表时间：
2008-10-13
影响因子：
--
通讯作者：
Wisnivesky, Juan
中科院分区：
文献类型：
--
作者：
McGinn, Thomas;O'Connor-Moore, Nicola;Wisnivesky, Juan
Background: Although hepatitis C virus (HCV) has an estimated national prevalence of 1.8%, testing rates are lower than those recommended by guidelines, particularly in primary care. A critical step is the ability to identify patients at increased risk who should be screened. We sought to prospectively derive and validate a clinical predication tool to assist primary care providers in identifying patients who should be tested for HCV antibodies.Methods: A total of 1000 randomly selected patients attending an inner-city primary care clinic filled out a 27-item questionnaire assessing 5 HCV risk factor domains: work, medical, exposure, personal care, and social history. Afterward, the patients underwent HCV antibody testing. Multivariable logistic regression analysis was performed to identify risk factors associated with HCV antibodies.Results: There was an 8.3% (95% confidence interval, 6.7%-10.2%) prevalence of HCV antibodies. The patients who were HCV antibody positive were more likely to be male, older, and insured by Medicaid (P
