REINDUCTION CHEMOTHERAPY IN SMALL-CELL LUNG-CANCER
REINDUCTION CHEMOTHERAPY IN SMALL-CELL LUNG-CANCER
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DOI：
10.1016/0277-5379(87)90452-4
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发表时间：
1987-11-01
期刊：
影响因子：
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通讯作者：
CALCIATI, A
中科院分区：
文献类型：
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作者：
GIACCONE, G;FERRATI, P;CALCIATI, A
13例对化疗有反应的小细胞肺癌患者在复发时使用相同的治疗方案，中位停药时间为30周。50%的人对再诱导作出反应；6例首次化疗完全缓解的患者中有2例在再诱导时再次获得完全缓解。从任何治疗开始的中位生存时间为94周。当诱导化疗有效且持续时间短时，复发时可以再次尝试相同的化疗并取得成功，这可能会影响复发的小细胞肺癌患者的生存。
Thirteen patients with small cell lung cancer responsive to chemotherapy were retreated with the same regimen at relapse, after a median off-therapy time of 30 weeks. Fifty per cent responded to reinduction; two out of six patients who had complete response to first chemotherapy obtained complete response again at reinduction. Median survival time from start of any therapy was 94 weeks. When induction chemotherapy has been effective and of short duration, the same chemotherapy can be attempted again with success at relapse and it may affect survival of relapsing small cell lung cancer patients.