Comparing breast cancer risk between lesbians and their heterosexual sisters
Comparing breast cancer risk between lesbians and their heterosexual sisters
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DOI：
10.1016/j.whi.2004.03.004
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发表时间：
2004-03-01
影响因子：
3.2
通讯作者：
Nussey, B
中科院分区：
文献类型：
--
作者：
Dibble, SL;Roberts, SA;Nussey, B
目的。本研究的目的是探讨女同性恋者及其异性恋姐妹在罹患乳腺癌的既定风险方面的异同。方法。本研究的设计是一项匹配（女同性恋与异性姐妹）横断面、回邮、匿名调查。我们将调查问卷分发给了整个加利福尼亚州的 40 岁及以上自称女同性恋的英语女性及其姐妹。使用修改后的盖尔乳腺癌风险模型以及其他与乳腺癌发生相关的既定因素，我们比较了 324 对姐妹 (N = 648) 的乳腺癌风险潜力。根据数据水平，使用配对 t 检验、协方差分析 (ANCOVA)、McNemar's X-2 或 Bowker 统计量对数据进行分析。主要发现。女同性恋者 5 年 (p < .0001) 和终生 (p = .001) 患乳腺癌的风险显着较高。女同性恋者预测乳腺癌发病率的原因很可能是她们在所有与妊娠相关的变量上得分较高，以及她们报告的乳腺活检数量相对较多。女同性恋者较少使用避孕药（p
Purpose. The purpose of this study was to explore the similarities and differences between lesbians and their heterosexual sisters in the established risks for developing breast cancer.Methods. The design for this study was a matched (lesbian with heterosexual sister) cross-sectional, mail-back, anonymous survey. We distributed the surveys throughout the state of California to English-speaking women who identified themselves as lesbians, age 40 and older, and their sisters. Using the modified Gail Breast Cancer Risk model as well as other well-established factors associated with the development of breast cancer, we compared the breast cancer risk potential for 324 sister pairs (N = 648). Data were analyzed using paired t-tests, analysis of covariance (ANCOVA), McNemar's X-2, or the Bowker statistic, as appropriate for the level of data.Main Findings. The lesbians had significantly higher 5-year (p < .0001) and lifetime (p = .001) risk for developing breast cancer. The reasons for lesbians' predicted rate of breast cancer were most likely their higher scores on all pregnancy-related variables and the relatively high number of breast biopsies they reported. The lesbians had used birth control pills less (p