Interspecific divergence, intrachromosomal recombination, and phylogenetic utility of Y-chromosomal genes in Drosophila
Interspecific divergence, intrachromosomal recombination, and phylogenetic utility of Y-chromosomal genes in Drosophila
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DOI：
10.1016/j.ympev.2005.10.006
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发表时间：
2006-03-01
影响因子：
4.1
通讯作者：
Barmina, O
中科院分区：
文献类型：
--
作者：
Kopp, A;Frank, AK;Barmina, O
重建最近分化的物种之间的系统发育关系是复杂的三个一般性问题：分离的多态性，早于物种分化，基因流期间和之后的物种形成，和基因座内重组。鉴于这些困难，Y染色体提供了几个重要的优势，其他基因组区域作为系统发育信息的来源。这些优点包括不存在重组、快速聚结和由于杂种雄性不育而减少种间渐渗的机会。在这份报告中，我们测试的Y染色体序列的系统发育效用在两组密切相关的部分互育果蝇物种。在地方bipectinata物种复合体，Y染色体位点明确恢复与以前的多位点分析和生殖关系最一致的遗传，并没有证据表明后物种的基因流或持久的祖先多态性。在地方在simulans物种复杂的情况下，由于至少一个Y-连锁基因区域的重复，随后重复基因之间的染色体内重组扰乱了它们的谱系，情况变得复杂。我们认为，Y染色体序列是一个有用的工具，用于解决最近分歧的物种之间的系统发育关系，特别是在男性异配子生物，符合Halfman的规则。然而，Y连锁基因的重复可能并不罕见，应特别注意区分直系同源和旁系同源序列。(c)2005年爱思唯尔公司All rights reserved.
Reconstruction of phylogenetic relationships among recently diverged species is complicated by three general problems: segregation of polymorphisms that pre-date species divergence, gene flow during and after speciation, and intra-locus recombination. In light of these difficulties, the Y chromosome offers several important advantages over other genomic regions as a source of phylogenetic information. These advantages include the absence of recombination, rapid coalescence, and reduced opportunity for interspecific introgression due to hybrid male sterility. In this report, we test the phylogenetic utility of Y-chromosomal sequences in two groups of closely related and partially inter-fertile Drosophila species. In the D. bipectinata species complex, Y-chromosomal loci unambiguously recover the phylogeny most consistent with previous multi-locus analysis and with reproductive relationships, and show no evidence of either post-speciation gene flow or persisting ancestral polymorphisms. In the D. simulans species complex, the situation is complicated by the duplication of at least one Y-linked gene region, followed by intrachromosomal recombination between the duplicate genes that scrambles their genealogy. We suggest that Y-chromosomal sequences are a useful tool for resolving phylogenetic relationships among recently diverged species, especially in male-heterogametic organisms that conform to Haldane's rule. However, duplication of Y-linked genes may not be uncommon, and special care should be taken to distinguish between orthologous and paralogous sequences. (c) 2005 Elsevier Inc. All rights reserved.