Exacerbation of obsessive compulsive disorder symptoms in children and adolescents during COVID-19 pandemic.
Exacerbation of obsessive compulsive disorder symptoms in children and adolescents during COVID-19 pandemic.
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DOI：
10.1016/j.psychres.2020.113363
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发表时间：
2020-11
影响因子：
11.3
通讯作者：
Coşkun M
中科院分区：
文献类型：
--
作者：
Tanir Y;Karayagmurlu A;Kaya İ;Kaynar TB;Türkmen G;Dambasan BN;Meral Y;Coşkun M
探讨COVID-19大流行和相关家庭隔离对强迫症（OCD）年轻受试者的症状特征、症状严重程度和强迫症症状加重及其相关因素的影响。通过电话或在线程序，在大学医院随访了初步诊断为强迫症的年轻受试者，以评估大流行期间的症状特征、症状严重程度和恶化程度。采用儿童耶鲁-布朗强迫症量表（CY-BOCS）和临床总体印象-严重程度量表（CGI-S）对大流行前和大流行期间的症状特征和严重程度进行评分。在大流行期间，污染强迫症（p=0.008）和清洁/洗涤强迫症（p=0.039）的频率显著增加。大流行期间CY-BOCS强迫（p<0.001）、强迫因子分（p<0.001）和总分（p<0.001）以及CGI-S评分（p<0.001）均高于大流行前。CY-BOCS评分的变化与社交环境中关于COVID-19的谈话/搜索、日常对COVID-19的关注、强迫症诊断的持续时间以及熟悉的人对COVID-19的诊断之间存在显著关系。在COVID-19大流行期间，患有强迫症的年轻受试者可能会出现其他症状，并使已有的强迫症症状恶化。
To investigate the effects of COVID-19 pandemic and related home confinement on symptom profile, symptom severity and exacerbation of obsessive compulsive disorder (OCD) symptoms and related factors among young subjects with OCD. Young subjects who have been followed up with a primary diagnosis of OCD in a university hospital were reached by telephone or online programs to assess symptom profile, symptom severity and exacerbation during pandemic. Children's Yale-Brown Obsessive Compulsive (CY-BOCS) and Clinical Global Impression- Severity (CGI-S) Scales were used to rate symptom profile and severity before pandemic and during pandemic periods. There was a significant increase in the frequency of contamination obsessions (p=0.008) and cleaning/washing compulsions (p=0.039) during pandemic period. CY-BOCS obsessions (p<0.001), compulsions subscales (p<0.001) and total scores (p<0.001), and CGI-S scores (p<0.001) during pandemic period were statistically higher than before pandemic period. There was a significant relationship between the change in CY-BOCS scores with talking/searching in the social environment about COVID-19, daily preoccupation about COVID-19, duration of OCD diagnosis and diagnosis of COVID-19 in someone familiar. Young subjects with OCD may develop additional symptoms and worsen already existing symptoms of OCD during COVID-19 pandemic.
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DOI：
10.1176/appi.ajp.2008.08020320
发表时间：
2008-12
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Bloch MH;Landeros-Weisenberger A;Rosario MC;Pittenger C;Leckman JF
通讯作者：
Leckman JF
影响因子：
2.7
作者：
Sprang, Ginny;Silman, Miriam
通讯作者：
Silman, Miriam
影响因子：
4.1
作者：
Wheaton, Michael G.;Abramowitz, Jonathan S.;Hale, Lisa R.
通讯作者：
Hale, Lisa R.
影响因子：
7.3
作者：
Yucelen, AG;Rodopman-Arman, A;Fisek, G
通讯作者：
Fisek, G
影响因子：
3.7
作者：
Gao, Junling;Zheng, Pinpin;Dai, Junming
通讯作者：
Dai, Junming