Structure and assembly of the native collagen fibril.
Structure and assembly of the native collagen fibril.
复制标题
天然胶原纤维的结构和组装。
DOI：
10.3109/03008208209034403
复制
发表时间：
1982
影响因子：
2.9
通讯作者：
K. Piez
中科院分区：
文献类型：
--
作者：
K. Piez
天然胶原原纤维的体外组装是一个多步骤的过程，包括未知结构的初始中间体，细丝的线性生长，形成原纤维的横向生长，以及共价交联的稳定。提出了一种纤维结构模型，该模型由五股微纤维的亚结构组成，这些微纤维被横向压缩以将分子置于近六边形晶格的横截面上。
Assembly in vitro of the native collagen fibril is a multistep process involving an initial intermediate of unknown structure, linear growth of thin filaments, lateral growth to form the fibril, and stabilization by covalent crosslinks. A model for the structure of the fibril is proposed consisting of a substructure of five-stranded microfibrils laterally compressed to place molecules in cross section on a near-hexagonal lattice.