Synthesis of Fused Heterocycles via One‐pot Oxidative O‐Arylation, Pd‐Catalyzed C(sp3)‐H Arylation
Synthesis of Fused Heterocycles via One‐pot Oxidative O‐Arylation, Pd‐Catalyzed C(sp3)‐H Arylation
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DOI：
10.1002/adsc.201700761
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发表时间：
2017-10
影响因子：
5.4
通讯作者：
F. Hong;Nannan Lu;Beili Lu;Jiajia Cheng
中科院分区：
文献类型：
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作者：
F. Hong;Nannan Lu;Beili Lu;Jiajia Cheng
通过对现成的芳醇和三价芳基碘试剂进行一锅氧化 O-芳基化、Pd 催化的 C(sp3)-H 芳基化，开发了一种高效且用户友好的 7H-色并[3,2-c]喹啉合成方法。各种有价值且复杂的稠合杂环以高分离产率和广泛的底物范围快速组装。
An efficient and user-friendly synthesis of 7H-chromeno[3,2-c]quinolines has been developed via a one-pot oxidative O-arylation, Pd-catalyzed C(sp3)-H arylation of readily available arylols and trivalent aryliodine reagents. A variety of valuable and complex fused heterocycles were quickly assembled in high isolated yields with broad substrate scopes.