Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo
Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo
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DOI：
10.1016/s0925-4773(02)00126-0
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发表时间：
2002-08-01
影响因子：
2.6
通讯作者：
Kola, I
中科院分区：
文献类型：
--
作者：
Ristevski, S;Tam, PPL;Kola, I
Ets2 is a member of the ETS family of transcription factors. In order to address the developmental function of Ets2, we have examined its expression pattern in E8.5 to E13.5 embryos using RNA whole-mount in situ hybridization. In the paraxial mesoderm, Ets2 is expressed uniformly in the presomitic mesoderm and then restricted to the cells in the rostral portion of the segmenting and the next two recently formed somites. In the developing limb, Ets2 expression in the mesenchyme reflects the progressive formation of the hand or foot plate and the digital skeleton. In addition, Ets2 is expressed in the otic vesicle and its derivatives, the dorsal (posterior) root ganglia, the neuroepithelium in the dorsal part of the caudal neural tube and the inter-segmental vasculature. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
