Circular RNA and tumor microenvironment
Circular RNA and tumor microenvironment
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DOI:
10.1186/s12935-020-01301-z
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发表时间:
2020
影响因子:
5.8
通讯作者:
Quan Liao
中科院分区:
文献类型:
--
作者:
Huixin Song;Qiaofei Liu;Quan Liao
AbstractCircular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes. The roles of circRNAs in cancers have gained increasing concerns. The communications between the cancer cells and tumor microenvironment (TME) play complicated roles to affect the malignant behaviors of cancers, which potentially present new therapeutic targets. Herein, we reviewed the roles of circRNAs in the TME.