Evaluation of the shape symmetry of bilateral normal corneas in a Chinese population.
Evaluation of the shape symmetry of bilateral normal corneas in a Chinese population.
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DOI：
10.1371/journal.pone.0073412
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Elsheikh A
中科院分区：
文献类型：
--
作者：
Bao F;Chen H;Yu Y;Yu J;Zhou S;Wang J;Wang Q;Elsheikh A
为了研究具有大范围曲率、散光和厚度值的正常角膜中整体角膜地形的双边对称性，使用 Pentacam 记录了 342 名参与者的前表面和后表面的横截面研究地形图像。将高程数据拟合到考虑平移和旋转位移的一般二次模型。对同侧角膜的角膜形状参数（高度、两个主要方向的半径 Rx 和 Ry，以及相应的形状因子 Qx 和 Qy）和角膜位置参数（平移位移：x0、y0 和 z0，以及旋转位移：α、β 和 γ）估计值的比较进行统计分析。一般二次模型提供了角膜前表面和后表面地形数据1.7±0.6 µm和5.7±1.3 µm的平均均方根拟合误差。比较显示出高度显着的双边相关性，同侧角膜之间在前表面和后表面的 Rx、Ry、Qx 和 Qy 方面的差异与零保持不显着差异。角膜中央和周边区域随机选择的点的高度测量的双边差异表明其他角膜之间存在强烈的镜像对称性。前后地形图中，左右角膜的平均几何中心（x0，y0，z0）分别位于顶点的颞侧和下颞侧。沿X轴的旋转位移角α在双侧角膜中具有相似的分布，而沿Y轴的旋转角β则显示双眼向鼻侧倾斜。此外，与角膜散光相关的沿Z轴的旋转角γ表现出明显的镜像对称性。角膜地形图分析表明双侧角膜之间存在强烈且具有统计学意义的镜像对称性。这一特性有助于检测病理异常、疾病诊断、测量验证和手术计划。
To investigate the bilateral symmetry of the global corneal topography in normal corneas with a wide range of curvature, astigmatism and thickness values Cross-Sectional Study Topography images were recorded for the anterior and posterior surfaces of 342 participants using a Pentacam. Elevation data were fitted to a general quadratic model that considered both translational and rotational displacements. Comparisons between fellow corneas of estimates of corneal shape parameters (elevation, radius in two main directions, Rx and Ry, and corresponding shape factors, Qx and Qy) and corneal position parameters (translational displacements: x0, y0 and z0, and rotational displacements: α, β and γ) were statistically analyzed. The general quadratic model provided average RMS of fit errors with the topography data of 1.7±0.6 µm and 5.7±1.3 µm in anterior and posterior corneal surfaces. The comparisons showed highly significant bilateral correlations with the differences between fellow corneas in Rx, Ry, Qx and Qy of anterior and posterior surfaces remaining insignificantly different from zero. Bilateral differences in elevation measurements at randomly-selected points in both corneal central and peripheral areas indicated strong mirror symmetry between fellow corneas. The mean geometric center (x0, y0, z0) of both right and left corneas was located on the temporal side and inferior-temporal side of the apex in anterior and posterior topography map, respectively. Rotational displacement angle α along X axis had similar distributions in bilateral corneas, while rotation angle β along Y axis showed both eyes tilting towards the nasal side. Further, rotation angle γ along Z axis, which is related to corneal astigmatism, showed clear mirror symmetry. Analysis of corneal topography demonstrated strong and statistically-significant mirror symmetry between bilateral corneas. This characteristic could help in detection of pathological abnormalities, disease diagnosis, measurement validation and surgery planning.
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影响因子：
2.9
作者：
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通讯作者：
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DOI：
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发表时间：
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