Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
复制标题
DOI：
10.1016/j.jvscit.2019.07.004
复制
发表时间：
2019-12-01
影响因子：
--
通讯作者：
Cameron, Scott J.
中科院分区：
文献类型：
--
作者：
Bishop, G. Jay;Gorski, Joshua;Cameron, Scott J.
一名49岁男性，在运动时出现进行性呼吸困难和晕厥病史，表现为低血压和急性右心室衰竭，最终诊断为急性肺栓塞。实验室数据显示活化部分凝血活酶时间延长，这混淆了治疗选择。他最终被诊断为抗磷脂综合征和因子XII缺乏症，并接受了血栓动脉内膜切除术，右心室衰竭和症状消退。仔细观察病史、最初的体格检查表现和临床资料往往能及时诊断和治疗慢性血栓栓塞性肺动脉高压。
A 49-year-old man with progressive dyspnea on exertion and a remote history of syncope presented with hypotension and acute right ventricular failure, and was ultimately diagnosed with acute pulmonary embolism. Laboratory data revealed a prolonged activated partial thromboplastin time, which confounded treatment options. He was ultimately diagnosed with anti-phospholipid syndrome and factor XII deficiency, and underwent a thromboendarterectomy procedure with resolution of right ventricular failure and symptoms. Careful attention to history, initial physical examination manifestations, and clinical data often permit a timely diagnosis of and treatment for chronic thromboembolic pulmonary hypertension.