Bone metabolism of residual ridge beneath the denture base of an RPD observed using NaF-PET/CT
Bone metabolism of residual ridge beneath the denture base of an RPD observed using NaF-PET/CT
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DOI：
10.1016/j.jpor.2011.04.002
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发表时间：
2012-01-01
影响因子：
3.6
通讯作者：
Sasaki, Keiichi
中科院分区：
文献类型：
--
作者：
Suenaga, Hanako;Yokoyama, Masayoshi;Sasaki, Keiichi
病人：患者女，66岁，双侧下颌无牙颌，无义齿修复经验，以左侧牙弓咀嚼功能障碍为主诉，选择单侧游离端可摘局部义齿（RPD）替代左下磨牙。在使用RPD前和使用RPD后1、6和13周，使用18氟NaF正电子发射计算机断层扫描（NaF-PET）/计算机断层扫描（CT）获得断层图像，以观察使用RPD引起的残余骨代谢变化。计算左下牙列缺失部位（试验侧）和右下牙列缺失部位（对照侧）的PET标准摄取值（SUV）和CT值。结果，对照侧的SUV在使用RPD后保持静止，而试验侧的SUV在使用RPD后1周和6周增加，然后下降。然而，CT图像显示RPD下方的骨形状和结构没有明显的变化，对照侧和试验侧的CT值也没有变化。讨论：本报告表明NaF-PET可以检测到RPD使用后不久的骨代谢变化，这是临床X射线无法检测到的。SUV的变化可能是一个机械生物学反应的压力，由于RPD的使用，和穿着的RPD可能会增加骨转换下denture.Conclusion：这份报告表明，穿着的RPD增加骨转换下义齿后立即RPD使用没有临床检测到的变化，骨结构或体积。(C)2011年日本口腔修复学会。由Elsevier爱尔兰出版。All rights reserved.
Patient: A 66-year-old woman, who had a bilateral free-end edentulous mandible and no experience with dentures, was examined for the chief complaint of masticatory dysfunction on left side of dental arch. A unilateral distal extension removable partial denture (RPD) replacing lower-left molars was selected. Tomographic images were obtained using Fluorine-18 NaF positron emission computerized tomography (NaF-PET)/computed tomography (CT) before the RPD use and at 1, 6, and 13 weeks after the RPD use to observe the metabolic changes in residual bone caused by the RPD use. PET standardized uptake values (SUVs) and CT values were calculated for lower-left edentulous site (test side) and lower-right edentulous site (control side). As a result, SUVs on the control side remained static after the RPD use, whereas those on the test side increased at 1 and 6 weeks after the RPD use and then decreased. However, CT images showed no obvious changes in the bone shape and structure beneath RPD, and CT values both on the control and test sides did not change either.Discussion: This report shows that NaF-PET could detect bone metabolic changes soon after the RPD use, which cannot be detected by clinical Xrays. The SUV changes may be a mechanobiological reaction to the pressure due to the RPD use, and wearing of the RPD may increase the bone turnover beneath denture.Conclusion: This report demonstrates that wearing of an RPD increases bone turnover beneath denture immediately after the RPD use without clinically detectable changes in bone structure or volume. (C) 2011 Japan Prosthodontic Society. Published by Elsevier Ireland. All rights reserved.