CHARACTERIZATION OF SEABUCKTHORN OIL EMULSION
CHARACTERIZATION OF SEABUCKTHORN OIL EMULSION
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DOI：
10.31482/mmsl.2012.007
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发表时间：
2012-06
期刊：
影响因子：
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通讯作者：
S. Cupara;S. Janković;I. Arsić;V. Tadić;V. Jaćević
中科院分区：
文献类型：
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作者：
S. Cupara;S. Janković;I. Arsić;V. Tadić;V. Jaćević
沙棘油外用尽管其对受损皮肤有益，但由于其为液态，因此很难清洗。为了克服这一不足，制备了沙棘油半固体乳剂。先前的研究表明，这种具有液晶增强结构的乳液显示出比沙棘油更高的伤口愈合潜力。本研究的目的是表征该乳剂局部使用的适用性。通过组合形成液晶的乳化剂来制备乳液。加入两种不同量的沙棘油。用10%和40%的沙棘油制备样品。感官特性通过目测和将样品涂抹在薄玻璃板上来估计。乳液的类型通过电导法确定，而乳液的pH值通过pH计测量。沙棘乳剂样品呈橙子，半固体，有光泽，易涂抹于皮肤上，玻璃板上涂抹均匀。不存在气味，并且乳液在施用到皮肤上之后可以用水冲洗，这是油/水乳液的期望特性。电导率的结果证实外相是水。样品具有可接受的外部局部使用pH值。确定了制备沙棘油半固体乳剂的配方和方法。感官特性、pH值和获得的乳剂的类型似乎足以用于局部使用。
External application of seabuckthorn oil (Hippophae rhamnoides L.) is difficult due to its liquid state in spite of its benefits for damaged skin. In order to overcome this inadequacy the semisolid emulsion with seabuckthorn oil was prepared. Previous research showed that this emulsion possessing an enhanced structure with liquid crystals showed a higher wound healing potential than seabuckthorn oil. The aim of this investigation was to characterize suitability of this emulsion for topical use. The emulsion was prepared by combining emulsifiers that form liquid crystals. Two different quantities of seabuckthorn oil were incorporated. Samples were prepared with 10% and 40% of seabuckthorn oil. Organoleptic characteristics were estimated visually and by smearing samples on a thin glass plate. Type of emulsion was determined by a conductometric method, while a pH value of the emulsion was measured by a pH meter. Samples of seabuckthorn emulsion were orange, semisolid, shiny, easily spreadable on skin, and the smear on the glass plate was homogeneous. There was an absence of smell and the emulsion could be rinsed by water after the application on skin, which is a desired characteristic of oil/water emulsions. Results of an electrical conductivity confirmed that an outer phase is water. Samples possesed an acceptable pH value for an external topical use. This research confirmed that constituents and a method used were suitable for preparing semisolid emulsion with seabuckthorn oil. Organoleptic properties, a pH value and a type of obtained emuslion appear to be adequate for topical use.