The find of COVID-19 vaccine: Challenges and opportunities.

The find of COVID-19 vaccine: Challenges and opportunities.
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COVID-19疫苗的发现:挑战与机遇。

DOI:
10.1016/j.jiph.2020.12.025
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发表时间:
2021-03
影响因子:
6.7
通讯作者:
Hutchinson A
Hutchinson A
中科院分区:
医学3区
文献类型:
--
作者:
ElBagoury M;Tolba MM;Nasser HA;Jabbar A;Elagouz AM;Aktham Y;Hutchinson A

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严重急性呼吸综合征冠状病毒(SARS-CoV-2)是一种新型冠状病毒,可引起具有流感样症状的COVID-19,是第三个千年第一次令人震惊的大流行。SARS-CoV-2属于β冠状病毒,即中东呼吸综合征冠状病毒(MERS-CoV)。COVID-19大流行给世界各地的社会经济生活造成了毁灭性的死亡和破坏性的特殊后果。因此,目前的审查将转向科学界,以全面了解SARS-CoV-2,以应对当前的大流行。通过本综述系统地显示,从公共卫生和传染性SARS-CoV-2疫苗发现的角度,它指标了COVID-19未满足的医学问题;目前正在研究治疗方案,下一步可能是疫苗。此外,审查报告广泛报告了实现“COVID-19/平坦曲线”的预防措施。结论是,强烈建议在本次大流行的特殊时间内配制疫苗,遵循以往大流行的相同规程;MERS-CoV和SARS-CoV,不包括疫苗接种开发过程的一些初始步骤。
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel corona virus, causing COVID-19 with Flu-like symptoms is the first alarming pandemic of the third millennium. SARS-CoV-2 belongs to beta coronavirus as Middle East respiratory syndrome coronavirus (MERS-CoV). Pandemic COVID-19 owes devastating mortality and destructively exceptional consequences on Socio-Economics life around the world. Therefore, the current review is redirected to the scientific community to owe comprehensive visualization about SARS-CoV-2 to tackle the current pandemic. As systematically shown through the current review, it indexes unmet medical problem of COVID-19 in view of public health and vaccination discovery for the infectious SARS-CoV-2; it is currently under-investigational therapeutic protocols, and next possible vaccines. Furthermore, the review extensively reports the precautionary measures to achieve" COVID-19/Flatten the curve". It is concluded that vaccines formulation within exceptional no time in this pandemic is highly recommended, via following the same protocols of previous pandemics; MERS-CoV and SARS-CoV, and excluding some initial steps of vaccination development process.
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