On-line monitoring human breath acetone during exercise and diet by proton transfer reaction mass spectrometry.
On-line monitoring human breath acetone during exercise and diet by proton transfer reaction mass spectrometry.
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DOI：
10.4155/bio-2018-0258
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发表时间：
2019-01
期刊：
影响因子：
1.8
通讯作者：
Xue Zou;Hongmei Wang;Dianlong Ge;Yan Lu;Lei Xia;Chaoqun Huang;Chengyin Shen;Y. Chu
中科院分区：
文献类型：
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作者：
Xue Zou;Hongmei Wang;Dianlong Ge;Yan Lu;Lei Xia;Chaoqun Huang;Chengyin Shen;Y. Chu
目的建立一种通过呼气丙酮监测脂肪减少的方法。方法采用直接呼吸采样系统与质子转移反应质谱（PTR-MS）相结合的方法对呼吸丙酮进行在线检测。对272名志愿者分别在运动和饮食时进行呼气丙酮检测。结果长期运动可使呼吸丙酮增加40- 130%。禁食一周的晚餐可以使它增加140%。结论运动和节食是减肥的有效方法。呼吸直接采样-质子转移反应质谱法测定呼吸中丙酮浓度，可为减肥运动和饮食方案的制定提供参考。
AIM This study aims to develop a method for monitoring fat loss by detection of breath acetone. METHODS A new method combining direct breath sampling system and proton transfer reaction MS (PTR-MS) was developed for on-line detection of breath acetone. The breath acetone of 272 volunteers was detected respectively when exercise or diet. RESULTS Exercises perennially can make the breath acetone increase by 40-130%. Dinner fasting for 1 week can make it increase by 140%. CONCLUSION Exercise and diet are two useful methods to lose fat. Determination of breath acetone concentration using the direct breath sampling system-proton transfer reaction MS can help design scheme of exercise and diet for losing weight.