Substance P release from K+-depolarized rat brain synaptosomes at one-second resolution.

Substance P release from K+-depolarized rat brain synaptosomes at one-second resolution.
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P 物质以一秒的分辨率从 K 去极化大鼠脑突触体中释放。

DOI:
10.1016/0006-8993(83)90202-0
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发表时间:
1983
期刊:
影响因子:
2.9
通讯作者:
Floor,E
Floor,E
中科院分区:
医学3区
文献类型:
--
作者:
Floor,E

文献摘要

相似文献

大鼠脑内分离的神经末梢(突触体)的P物质释放主要发生在持续K+去极化的第1秒内。K+或Ca~(2+)浓度降低,P物质释放较少,但释放时间相似。因此,P物质的快速释放发生在广泛的去极化条件下。
Substance P release from isolated nerve endings (synaptosomes) prepared from rat brain occured primarily within the first second of continuous K+-depolarization. If the concentrations of K+or Ca2+were decreased there was less substance P release, but the time course of release was similar. Thus the rapid release of substance P occurs over a wide range of depolarization conditions.