Necrotizing ulcerative gingivitis in beagle dogs. III. Distribution of spirochetes in interdental gingival tissue.
Necrotizing ulcerative gingivitis in beagle dogs. III. Distribution of spirochetes in interdental gingival tissue.
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比格犬的坏死性溃疡性牙龈炎。
DOI：
10.1111/j.1600-0765.1985.tb00836.x
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发表时间：
1985
影响因子：
3.5
通讯作者：
F. Kuijpers
中科院分区：
文献类型：
--
作者：
J. Maltha;F. Mikx;F. Kuijpers
本文报道了一种新的Warthin螺旋体染色方法，用于在光镜水平上研究螺旋体在诱发坏死性溃疡性牙龈炎的比格犬牙龈组织中的分布。螺旋体存在于溃疡部位的细胞渗出液中、溃疡附近的水肿上皮中以及完整的沟上皮中。它们似乎没有通过溃疡穿透结缔组织。这些观察结果表明，在NUG的病因学，螺旋体发挥的作用，在启动的病理过程中渗透的细胞间隙上皮。
A new modification of the Warthin spirochete staining method was developed to study at the light microscopic level the distribution of spirochetes in gingival tissues of beagle dogs with induced necrotizing ulcerative gingivitis. Spirochetes were present in cellular exudate at ulcerated sites, in edematous epithelium in the vicinity of ulcerations, and in intact sulcular epithelium. They did not appear to penetrate connective tissues via the ulcerations. These observations suggest that, in the etiology of NUG, spirochetes play a role in the initiation of the pathologic process by penetration of the intercellular spaces in the epithelium.