The Molecular Bacterial Load Assay Replaces Solid Culture for Measuring Early Bactericidal Response to Antituberculosis Treatment

The Molecular Bacterial Load Assay Replaces Solid Culture for Measuring Early Bactericidal Response to Antituberculosis Treatment
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DOI:
10.1128/jcm.01128-14
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发表时间:
2014-08-01
影响因子:
9.4
通讯作者:
Heinrich, Norbert
Heinrich, Norbert
中科院分区:
医学2区
文献类型:
--
作者:
Honeyborne, Isobella;Mtafya, Bariki;Heinrich, Norbert

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通过与固体琼脂和液体培养的比较,我们评价了分子细菌负荷法(MBL)在检测痰中结核分枝杆菌活性方面的应用。MBL检测提供了有关细菌负荷下降速度的早期信息,并且比任何一种形式的培养都具有技术优势。
We evaluated the use of the molecular bacterial load (MBL) assay, for measuring viable Mycobacterium tuberculosis in sputum, in comparison with solid agar and liquid culture. The MBL assay provides early information on the rate of decline in bacterial load and has technical advantages over culture in either form.