Concentrations of serum vitamin D and the metabolic syndrome among US adults
Concentrations of serum vitamin D and the metabolic syndrome among US adults
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DOI：
10.2337/diacare.28.5.1228
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发表时间：
2005-05-01
期刊：
影响因子：
16.2
通讯作者：
Liu, S
中科院分区：
文献类型：
--
作者：
Ford, ES;Ajani, UA;Liu, S
越来越多的研究表明，循环中的维生素D浓度可能与糖尿病的患病率(1-4)、葡萄糖浓度(4-8)以及胰岛素抵抗(4、5、8、9)呈负相关。此外，维生素D缺乏可能是代谢综合征的风险因素(8，10)，代谢综合征在美国成年人中高度流行(11)。然而，关于维生素D状态和代谢综合征之间的关系，仍有许多需要了解。由于这个话题几乎没有受到关注，而且现有的信息来自一个小的临床样本，我们试图在一个具有全国代表性的美国人口大样本中检查血清维生素D浓度和代谢综合征之间的联系的性质和强度。
Accumulating research suggests that circulating concentrations of vitamin D may be inversely related to the prevalence of diabetes (1-4), to the concentration of glucose (4-8), and to insulin resistance (4,5,8,9). In addition, vitanim D deficiency may be a risk factor for the metabolic syndrome (8,10), a highly prevalent condition among U.S. adults (11). Much remains to be learned, however, about the relationship between vitamin D status and metabolic syndrome. Because this topic has received scant attention and the available information was derived from a small clinically based sample, we sought to examine the nature and strength of the association between serum concentrations of vitamin D and the metabolic syndrome in a large nationally representative sample of the U.S. population.