Indium-alkene complex ions as reagents for selective chemical ionization.
Indium-alkene complex ions as reagents for selective chemical ionization.
复制标题
铟-烯烃络离子作为选择性化学电离试剂。
DOI：
10.1021/ac00176a018
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发表时间：
1989
影响因子：
7.4
通讯作者：
Wilkins,CL
中科院分区：
文献类型：
--
作者：
Chowdhury,AK;Cooper,JR;Wilkins,CL
混合物的化学电离（Cl）质谱分析的一个主要分析目标是选择性地分离组分，同时最大限度地减少碎片和化学干扰。为了使这种分析可行，适当的特定化学电离试剂是必要的，并应提供明确的分子量信息和定量目标化合物分析的能力。选择性化学电离也可以作为混合物的串联质谱分析（MS/MS）的第一步，其中结构解析是目标。尽管化学电离选择性试剂的开发已经取得了很大进展，但它们在直接混合物分析中的应用仍然相对未被探索。使用金属或金属络合离子作为Cl试剂正在成为当前研究兴趣活跃的领域（2-9）。我们最近建议（10）铟-烯烃络合离子可能有希望作为选择性化学电离质谱的试剂。在这里，我们证明了这种方法的潜力，将其应用到分析的模型混合物和无铅汽油样品使用InC 3 He+通过激光解吸傅里叶变换质谱（LD-FTMS）作为化学电离试剂。
A major analytical goal of chemical ionization (Cl) mass spectrometric analysis of mixtures is to selectively ionize components while minimizing fragmentation and chemical interferences. For such analyses to be feasible, suitably specific chemical ionization reagents are necessary and should provide both unambiguous molecular weight information and the capability for quantitative target compoundanalysis. Selective chemical ionization also can serve as the first step in tandem mass spectrometric analyses (MS/MS) of mixtures where structure elucidation is the goal. Although there has been a good deal of progress in development of selective reagents for chemical ionization (1), their applications to direct mixture analysis are still relatively unexplored. Use of metals or metal complex ions as Cl reagents is emerging as an area of active current research interest (2-9). We recently suggested (10) that indium-alkene complex ions might be promising as reagents for selective chemicalionization mass spectrometry. Here, we demonstrate the potential of this method by applying it to analysis of a model mixture and to an unleaded gasoline sample using InC3He+ generated via laser desorption Fourier transform mass spectrometry (LD-FTMS) as a chemical ionization reagent.