In vivo estimates of the position of advanced bionics electrode arrays in the human cochlea
In vivo estimates of the position of advanced bionics electrode arrays in the human cochlea
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DOI：
10.1177/000348940711600401
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发表时间：
2007-04-01
影响因子：
1.4
通讯作者：
Finley, Charles C.
中科院分区：
文献类型：
--
作者：
Skinner, Margaret W.;Holden, Timothy A.;Finley, Charles C.
目的：描述了一种用于确定耳蜗中每个电极位置的新技术，并将其应用于植入Advanced Bionics HiFocus I、Ij或Hysteresis阵列的15名患者的螺旋计算机断层扫描数据。使用ANALYZE成像软件配准来自患者术前和术后扫描以及来自临床扫描未植入耳朵的单个身体供体的三维图像体积，显微计算机断层扫描和正交平面荧光光学切片（OPFOS）显微镜。通过使用该配准，我们将身体供体耳蜗内的软组织的OPFOS图像的图谱与患者扫描数据中可用的骨和流体/组织边界进行比较，以选择蜗轴中轴位置并判断鼓阶或前庭阶中的电极位置，包括到内侧和外侧标量壁的距离。角旋转0度的起始点是一条线，连接中蜗轴和中间的耳蜗管入口从vestible.Results：该组平均阵列插入深度为477度（范围，286度至655度）。单词得分呈负相关（r = -0.59; p = .028）与在阶vestibuli.Conclusions电极的数量：虽然在所有措施的个体变异性是大的，重复模式的次优电极放置观察跨学科，强调这种技术的适用性。
Objectives: A new technique for determining the position of each electrode in the cochlea is described and applied to spiral computed tomography data from 15 patients implanted with Advanced Bionics HiFocus I, Ij, or Helix arrays.Methods: ANALYZE imaging software was used to register 3-dimensional image volumes from patients' preoperative and postoperative scans and from a single body donor whose unimplanted ears were scanned clinically, with micro computed tomography and with orthogonal-plane fluorescence optical sectioning (OPFOS) microscopy. By use of this registration, we compared the atlas of OPFOS images of soft tissue within the body donor's cochlea with the bone and fluid/tissue boundary available in patient scan data to choose the midmodiolar axis position and judge the electrode position in the scala tympani or scala vestibuli, including the distance to the medial and lateral scalar walls. The angular rotation 0 degrees start point is a line joining the midmodiolar axis and the middle of the cochlear canal entry from the vestibule.Results: The group mean array insertion depth was 477 degrees (range, 286 degrees to 655 degrees). The word scores were negatively correlated (r = -0.59; p = .028) with the number of electrodes in the scala vestibuli.Conclusions: Although the individual variability in all measures was large, repeated patterns of suboptimal electrode placement were observed across subjects, underscoring the applicability of this technique.