Structural informatics and its applications in medicine and biology.
Structural informatics and its applications in medicine and biology.
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结构信息学及其在医学和生物学中的应用。
DOI:
10.1097/00001888-199110000-00005
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发表时间:
1991
期刊:
影响因子:
--
通讯作者:
Brinkley,JF
中科院分区:
文献类型:
--
作者:
Brinkley,JF
The amount of information generated in all fields of science, particularly medicine and biology, is exponentially increasing. This trend, plus rapid advances in com-puter hardware, has led to the emergence of the field of informatics and, within the medical arena, medical informatics. Blois and Shortliffe define medical informatics as “the rapidly developing scientific field that deals with the storage, retrieval, and optimal use of biomedical information, data, and knowledge for problem solving and decision making." Although most medical informatics research has concen-trated on clinical applications (eg, medical records, hospital information systems, radiology systems, and pharmacy systems),* there is nothing in the definition to limit the field to clinical medicine. In fact, the definition implies that medical informatics covers the entire spectrum of information within a medical center, including basic science as well as clinical medicine. This broad interpretation is reasonable because clinical decision-mak-ing relies on information at the basic science level." An important type of basic medical in-formation is structural data and knowl-edge describing objects at the gross anatomic, cellular, and molecular levels. Accordingly, the National Library of Medicine has recognized the emergence of a subdiscipline of medical informatics, called “structural informatics,” that deals with the “... computerized representation of biomedical structural data, and its linkage to related text and numeric data.”* I will expand on this definition and show how structural informatics re-search applies to problems in medicine and biology.