Neuromuscular complications of hematopoietic stem cell transplantation
Neuromuscular complications of hematopoietic stem cell transplantation
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DOI：
10.1002/mus.24724
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发表时间：
2015-10
期刊：
影响因子：
3.4
通讯作者：
Katherine Ruzhansky;T. Brannagan
中科院分区：
文献类型：
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作者：
Katherine Ruzhansky;T. Brannagan
多发性肌炎、皮肌炎、周围神经病和神经肌肉传递障碍等神经肌肉疾病是造血干细胞移植(HSCT)的并发症。虽然在慢性移植物抗宿主病的背景下已有异基因HSCT病例的报道，但也已知这些病例在没有证据的情况下发生，甚至发生在自体HSCT的背景下。2005年美国国立卫生研究院的共识标准将多发性肌炎和皮肌炎归类为“独特”特征，将神经病和MG归类为“其他”特征。这些神经肌肉并发症与特发性自身免疫性疾病非常相似，对类似的治疗方式也有反应。肌肉神经，2015肌肉神经52：480-487,2015
Neuromuscular diseases such as polymyositis, dermatomyositis, peripheral neuropathy, and disorders of neuromuscular transmission are reported to be complications of hematopoietic stem cell transplantation (HSCT). Although cases have been reported with allogeneic HSCT in the setting of chronic graft versus host disease, they are also known to occur without evidence thereof and even occur in the setting of autologous HSCT. The 2005 National Institutes of Health Consensus Criteria classify polymyositis and dermatomyositis as “distinctive” features, and neuropathy and MG as “other” features. These neuromuscular complications present very similarly to the idiopathic autoimmune disorders and respond to similar treatment modalities. Muscle Nerve, 2015 Muscle Nerve 52: 480–487, 2015