KMgene: a unified R package for gene-based association analysis for complex traits.

KMgene: a unified R package for gene-based association analysis for complex traits.
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DOI:
10.1093/bioinformatics/bty066
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发表时间:
2018-06-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Chen W
Chen W
中科院分区:
其他
文献类型:
--
作者:
Yan Q;Fang Z;Chen W

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在这份报告中,我们介绍了一个R包KMgene进行基于基因的关联测试的家族,多变量或纵向性状使用内核机(KM)回归广义线性混合模型框架下。进行了大量的模拟,以评估在KMgene中实施的方法的有效性。 http://cran.r-project.org/web/packages/KMgene. 补充数据可在Bioinformatics在线获得。
In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity of the approaches implemented in KMgene. http://cran.r-project.org/web/packages/KMgene. Supplementary data are available at Bioinformatics online.
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