Menthol Content in US Marketed Cigarettes

Menthol Content in US Marketed Cigarettes
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DOI:
10.1093/ntr/ntv162
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发表时间:
2016-07-01
影响因子:
4.7
通讯作者:
Holman, Matthew R.
Holman, Matthew R.
中科院分区:
医学2区
文献类型:
--
作者:
Ai, Jiu;Taylor, Kenneth M.;Holman, Matthew R.

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2011年,薄荷醇卷烟占美国市场的32%,但很少有文献报告提供商业卷烟的薄荷醇测量数据。为了评估目前美国卷烟市场上薄荷醇的应用水平,我们测定了各种当代家用卷烟产品中标记或未标记含有薄荷醇的卷烟中的薄荷醇水平。我们使用经验证的气相色谱/质谱法测量了45支整支卷烟的薄荷醇含量。在23个标记为薄荷醇产品的卷烟品牌中,整支香烟的薄荷醇含量范围为2.9 - 19.6mg/支,其中三种产品的薄荷醇含量高于其它薄荷醇产品。22种未标明含有薄荷醇的卷烟产品的薄荷醇含量范围为0.002至0.07毫克/支。根据目前有限的数据,给定香烟产品的包装类型(软包装与硬包装)似乎不会影响薄荷醇水平。标记为含有薄荷醇的香烟产品中的薄荷醇水平比未标记为含有薄荷醇的香烟产品高约50至5000倍。一般来说,薄荷醇含量似乎出现在离散范围内的薄荷醇和nonmentholated cigarettes.This研究表明,薄荷醇可能存在于nonmentholated cigarettes,并增加了如何薄荷醇可能用于卷烟产品的理解。这是同一实验室的第一项系统性研究,可以很容易地比较薄荷醇和非薄荷醇香烟。
In 2011 menthol cigarettes accounted for 32 percent of the market in the United States, but there are few literature reports that provide measured menthol data for commercial cigarettes. To assess current menthol application levels in the US cigarette market, menthol levels in cigarettes labeled or not labeled to contain menthol was determined for a variety of contemporary domestic cigarette products.We measured the menthol content of 45 whole cigarettes using a validated gas chromatography/mass spectrometry method.In 23 cigarette brands labeled as menthol products, the menthol levels of the whole cigarette ranged from 2.9 to 19.6mg/cigarette, with three products having higher levels of menthol relative to the other menthol products. The menthol levels for 22 cigarette products not labeled to contain menthol ranged from 0.002 to 0.07mg/cigarette. The type of packaging (soft vs. hard pack) for a given cigarette product does not appear to affect menthol levels based on the current limited data.Menthol levels in cigarette products labeled as containing menthol are approximately 50- to 5000-fold higher than those in cigarette products not labeled as containing menthol. In general, menthol content appears to occur within discrete ranges for both mentholated and nonmentholated cigarettes.This study shows that menthol may be present in non-mentholated cigarettes and adds to the understanding of how menthol may be used in cigarette products. It is the first systematic study from the same laboratory which will readily enable comparison among menthol and non-menthol cigarettes.