Effect of Glycerophospholipid Class on the β-Carotene Uptake by Human Intestinal Caco-2 Cells
Effect of Glycerophospholipid Class on the β-Carotene Uptake by Human Intestinal Caco-2 Cells
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DOI：
10.1271/bbb.90665
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发表时间：
2010-01-01
影响因子：
1.6
通讯作者：
Nagao, Akihiko
中科院分区：
文献类型：
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作者：
Kotake-Nara, Eiichi;Yonekura, Lina;Nagao, Akihiko
评估了各种甘油磷脂对人肠 Caco-2 细胞摄取溶解在混合胶束中的 β-胡萝卜素的影响。磷脂酰乙醇胺显着增强β-胡萝卜素从胶束到细胞的转移，而磷脂酰胆碱则抑制它。无论极性头基如何，所有溶甘油磷脂都增强了转移。因此，甘油磷脂有可能改变类胡萝卜素的肠道吸收。
The effects were evaluated of various glycerophospholipids on the uptake of beta-carotene solubilized in mixed micelles by human intestinal Caco-2 cells. Phosphatidylethanolamine markedly enhanced the transfer of beta-carotene from the micelles to the cells, whereas phosphatidyleholine suppressed it. All the lysoglycerophospholipids enhanced the transfer, irrespective of the polar head group. Glycerophospholipids therefore have the potential to modify the intestinal absorption of carotenoids.