Effect of Sleep Extension on the Subsequent Testosterone, Cortisol and Prolactin Responses to Total Sleep Deprivation and Recovery
Effect of Sleep Extension on the Subsequent Testosterone, Cortisol and Prolactin Responses to Total Sleep Deprivation and Recovery
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DOI：
10.1111/jne.12346
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发表时间：
2016-02-01
影响因子：
3.2
通讯作者：
Chennaoui, M.
中科院分区：
文献类型：
--
作者：
Arnal, P. J.;Drogou, C.;Chennaoui, M.
Total sleep deprivation (TSD) in humans is associated with altered hormonal levels, which may have clinical relevance. Less is known about the effect of an extended sleep period before TSD on these hormonal changes. Fourteen subjects participated in two experimental counterbalanced conditions (randomised cross-over design): extended sleep (21.00-07.00h time in bed, EXT) and habitual sleep (22.30-07.00h time in bed, HAB). For each condition, subjects performed two consecutive phases: six nights of either EXT or HAB. These nights were followed by 3days in the sleep laboratory with blood sampling at 07.00 and 17.00h at baseline (B-07.00 and B-17.00), after 24 and 34h of continuous awakening (24h-CA, 34h-CA) and after one night of recovery sleep (R-07.00 and R-17.00) to assess testosterone, cortisol, prolactin and catecholamines concentrations. At 24h of awakening, testosterone, cortisol and prolactin concentrations were significantly lower compared to B-07.00 and recovered basal levels after recovery sleep at R-07.00 (P
