Immunomodulatory constituents from an ascomycete, Chaetomium seminudum
Immunomodulatory constituents from an ascomycete, Chaetomium seminudum
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DOI：
10.1021/np0302201
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发表时间：
2004-01-01
影响因子：
5.1
通讯作者：
Ishibashi, M
中科院分区：
文献类型：
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作者：
Fujimoto, H;Sumino, M;Ishibashi, M
一项针对子囊菌 (Chaetomium seminudum) 的 EtOAc 提取物的免疫调节活性的筛选研究，提供了一种已知的表聚硫二氧代哌嗪 chetomin (1)，以及三种新的 chetomin 相关代谢物，名为 chetoseminudins A (2)、B (3) 和 C (4)。在这四种代谢物中，I和2被推断为该真菌的免疫抑制特征。
A screening study focusing on immunomodulatory activity of the EtOAc extract of an Ascomycete, Chaetomium seminudum, has afforded a known epipolythiodioxopiperazine, chetomin (1), together with three new chetomin-related metabolites named chetoseminudins A (2), B (3), and C (4). Among these four metabolites, I and 2 have been deduced as the immunosuppressive features of this fungus.