New flavins for old: artificial flavins as active site probes of flavoproteins.
New flavins for old: artificial flavins as active site probes of flavoproteins.
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新黄素代替旧黄素：作为黄素蛋白活性位点探针的人工黄素。
作者：
S. Ghisla;V. Massey
黄素酶作为生物催化剂的独特之处在于它们能够执行多种不同的生化过程。这使它们与使用其他辅酶的酶不同，例如吡啶核苷酸、磷酸吡哆醛或焦磷酸硫胺素，每种辅酶都涉及单一类型的化学事件。因此，黄素参与多种底物的脱氢、单电子传输过程、分子氧的活化、生物光的发射（生物发光）、光生物化学过程（例如向光性），并且可能参与涉及酶功能控制的过程。为了
Flavin enzymes are unique as biological catalysts in that they carry out a wide variety of different biochemical processes. This sets them apart from enzymes which use other coenzymes, like pyridine nucleotides, pyridoxal phosphate or thiamin pyrophosphate, each of which involves a single type of chemical event. Flavins thus are involved in the dehydrogenation of a variety of substrates, in one-electron transport processes, in the activation of molecular oxygen, in the emission of biological light (bioluminescence), in photobiochemical processes (e.g. phototropism), and probably in processes involving control of enzymic functions. For