Sustainable Synthesis of Renewable Terpenoid-Based (Meth)acrylates Using the CHEM21 Green Metrics Toolkit
Sustainable Synthesis of Renewable Terpenoid-Based (Meth)acrylates Using the CHEM21 Green Metrics Toolkit
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DOI：
10.1021/acssuschemeng.9b01578
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发表时间：
2019-07-01
影响因子：
8.4
通讯作者：
Du Prez, Filip E.
中科院分区：
文献类型：
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作者：
Droesbeke, Martijn A.;Du Prez, Filip E.
萜烯及其亚类萜类化合物是从各种植物和树木中提取的天然产物。由于其结构的多样性，它们在合成聚合物中提供了多种功能化的可能性。本研究旨在通过广泛报道或不太传统的方法合成一系列萜烯基（甲基）丙烯酸酯，并根据其绿色证书筛选这些不同的合成方法。潜在的目标是在最近开发的CHEM21绿色指标工具包的帮助下，定性和定量地确定最有效的原子和可持续的途径。同时，这项研究显示了该评估系统的易用性，并鼓励该工具包不仅在聚合物科学中，而且在化学的其他领域得到更广泛的使用。
Terpenes and their subclass terpenoids are natural products, extracted from various plants and trees. As a result of their structural diversity, they offer versatile functionalization possibilities when incorporated into synthetic polymers. This investigation aims at synthesizing a range of terpenoid-based (meth)acrylates via widely reported or less conventional methods and at screening these different synthetic methodologies in terms of their green credentials. The underlying goal has been to both qualitatively and quantitatively determine the most atom efficient and sustainable pathway with the help of the recently developed CHEM21 green metrics toolkit. At the same time, this study shows the ease of this evaluation system and encourages a more widespread use of this toolkit not only in polymer science but also in other areas of chemistry.