Prevalence and initial prescription of psychotropics in patients with common cancers in Japan, based on a nationwide health insurance claims database
Prevalence and initial prescription of psychotropics in patients with common cancers in Japan, based on a nationwide health insurance claims database
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DOI：
10.1002/pon.4511
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发表时间：
2018-02-01
期刊：
影响因子：
3.6
通讯作者：
Kawakami, Koji
中科院分区：
文献类型：
--
作者：
Sato, Izumi;Onishi, Hideki;Kawakami, Koji
目的调查新诊断的 8 种常见癌症患者中精神药物的使用情况，并确定影响精神药物处方的因素。方法这项回顾性描述性研究检查了 2009 年 7 月至 2014 年 5 月期间新诊断的乳腺癌、结直肠癌、肝癌、肺癌、卵巢癌、胰腺癌、前列腺癌或胃癌患者的数据。这些数据来自全国健康声明数据库。按癌症类型分析癌症诊断后13个月内所有口服精神药物的初始处方比例；使用多变量逻辑回归模型计算开精神药物的优势比（OR）。结果共有 14661 名患者新诊断患有癌症。为 6593 名 (45%) 患者开了精神药物。肺癌（62.6%）和前列腺癌（35.1%）患者的精神药物处方比例最高和最低。精神药物处方的最强预测因素是化疗（OR，2.59；95% 置信区间 [CI]，2.31-2.91；P
ObjectiveTo investigate the prevalence of psychotropic medication use and identify factors affecting the prescription of psychotropics among patients newly diagnosed with any of 8 common types of cancer.MethodsThis retrospective descriptive study examined data for patients newly diagnosed with breast, colorectal, liver, lung, ovarian, pancreatic, prostate, or stomach cancer between July 2009 and May 2014. The data were derived from a nationwide health claims database. The proportion of initial prescriptions for all oral psychotropics within 13months of cancer diagnosis was analyzed by cancer type; the odds ratio (OR) for prescribing psychotropics was calculated using multivariable logistic regression models.ResultsA total of 14661 patients were newly diagnosed with cancer. Psychotropics were prescribed for 6593 (45%) patients. The highest and lowest proportions of psychotropic prescriptions were recorded for patients with lung cancer (62.6%) and prostate cancer (35.1%), respectively. The strongest predictors for psychotropic prescriptions were chemotherapy (OR, 2.59; 95% confidence interval [CI], 2.31-2.91; P