LATITUDE GRADIENTS IN MELANOMA INCIDENCE AND MORTALITY IN THE NON-MAORI POPULATION OF NEW-ZEALAND
LATITUDE GRADIENTS IN MELANOMA INCIDENCE AND MORTALITY IN THE NON-MAORI POPULATION OF NEW-ZEALAND
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DOI：
10.1007/bf01830242
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发表时间：
1994-05-01
影响因子：
2.3
通讯作者：
ELWOOD, JM
中科院分区：
文献类型：
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作者：
BULLIARD, JL;COX, B;ELWOOD, JM
对新西兰非毛利人皮肤恶性黑色素瘤(CMM)发病率和死亡率随纬度的变化进行了评估。对于年龄在20-74岁之间的人群，年龄、时间段、出生队列、性别和地区(纬度)的影响以及它们之间的一些交互作用被用对数线性回归方法进行了评估。男性和女性的年龄标化发病率和死亡率随着越来越接近赤道而增加。男性的这些纬度梯度大于女性。新西兰最南端(北纬44度-S)与最北端(北纬36度-S)相比，患黑色素瘤的相对风险为0.63(95%可信区间[CI]=0.60-0.67)，死亡率的相对风险为0.76(CI=0.68-0.86)。男性每度纬度CMM比率的平均百分比变化比其他已发表的研究报告的更大。男性和女性在黑色素瘤风险与纬度上的差异表明，地区性太阳行为模式或其他风险因素可能有助于观察到的纬度梯度。
The variation with latitude of incidence and mortality for cutaneous malignant melanoma (CMM) in the non-Maori population of New Zealand was assessed. For those aged 20 to 74 years, the effects of age, time period, birth-cohort, gender, and region (latitude), and some interactions between them were evaluated by loglinear regression methods. Increasing age-standardized incidence and mortality rates with increasing proximity to the equator were found for men and women. These latitude gradients were greater for males than females. The relative risk of melanoma in the most southern part of New Zealand (latitude 44-degrees-S) compared with the most northern region (latitude 36-degrees-S) was 0.63 (95 percent confidence interval [CI] = 0.60-0.67) for incidence and 0.76 (CI = 0.68-0.86) for mortality, both genders combined. The mean percentage change in CMM rates per degree of latitude for males was greater than those reported in other published studies. Differences between men and women in melanoma risk with latitude suggest that regional sun-behavior patterns or other risk factors may contribute to the latitude gradient observed.