ReviewReview: Oxidative Injury to the Vascular Endothelium
ReviewReview: Oxidative Injury to the Vascular Endothelium
复制标题
回顾回顾:血管内皮的氧化损伤
DOI:
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发表时间:
1986
期刊:
影响因子:
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通讯作者:
P. Ward
中科院分区:
文献类型:
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作者:
J. Warren;P. Ward
In recent years, increasing clinical and experimental data have provided compelling evidence that neutrophil-derived oxygen radicals and their metabolites are important mediators of vascular endothelial injury. In this review, attention is directed toward in vitro, ex vivo, and in vivo experimental studies contributing to current understanding of mechanisms of oxyradical mediated endothelial damage. Although these studies may have broad significance, they appear to have particular relevance to the pathogenesis of the adult respiratory distress syndrome and other types of acute pulmonary dysfunction.