Walking enhances peripheral visual processing in humans
Walking enhances peripheral visual processing in humans
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DOI：
10.1371/journal.pbio.3000511
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发表时间：
2019-10-01
期刊：
影响因子：
9.8
通讯作者：
Haendel, Barbara
中科院分区：
文献类型：
--
作者：
Cao, Liyu;Haendel, Barbara
认知过程几乎只在高度控制的环境下进行研究，在这种环境下，自愿的身体运动被抑制。然而，最近的动物实验表明，运动和静止之间的早期视觉区域的神经反应发生了巨大变化，从而表明运动状态之间的感觉处理存在差异。运动是否也能调节人类的视觉皮层活动，其知觉后果是什么？我们的研究表明，步行增加了周围视觉输入对中央视觉输入的对比度依赖性影响。这种增加在刺激锁定脑电图（EEG）反应（稳态视觉诱发电位[SSVEP]）和知觉表现中普遍存在。持续的α振荡（约10 Hz）进一步与步行诱导的SSVEP振幅变化呈正相关，表明步行过程中参与了改变的抑制过程。研究结果预测，步行会增加对周边视觉输入的处理。第二项研究确实表明，当受试者行走时，他们对外围刺激的对比敏感度高于中枢刺激。我们的工作显示了互补的神经生理学和行为证据，证实了动物的发现，即步行导致人类早期视觉神经元活动的变化。行走引起的神经元调节确实与特定的感知变化有关，这扩展了现有的动物研究。
Cognitive processes are almost exclusively investigated under highly controlled settings during which voluntary body movements are suppressed. However, recent animal work suggests differences in sensory processing between movement states by showing drastically changed neural responses in early visual areas between locomotion and stillness. Does locomotion also modulate visual cortical activity in humans, and what are the perceptual consequences? Our study shows that walking increased the contrast-dependent influence of peripheral visual input on central visual input. This increase is prevalent in stimulus-locked electroencephalogram (EEG) responses (steady-state visual evoked potential [SSVEP]) alongside perceptual performance. Ongoing alpha oscillations (approximately 10 Hz) further positively correlated with the walking-induced changes of SSVEP amplitude, indicating the involvement of an altered inhibitory process during walking. The results predicted that walking leads to an increased processing of peripheral visual input. A second study indeed showed an increased contrast sensitivity for peripheral compared to central stimuli when subjects were walking. Our work shows complementary neurophysiological and behavioural evidence corroborating animal findings that walking leads to a change in early visual neuronal activity in humans. That neuronal modulation due to walking is indeed linked to specific perceptual changes extends the existing animal work.