Relationship of physical activity and body mass index to the risk of hypertension: A prospective study in Finland

Relationship of physical activity and body mass index to the risk of hypertension: A prospective study in Finland
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DOI:
10.1161/01.hyp.0000107400.72456.19
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发表时间:
2004-01-01
期刊:
影响因子:
8.3
通讯作者:
Jousilahti, P
Jousilahti, P
中科院分区:
医学1区
文献类型:
--
作者:
Hu, G;Barengo, NC;Jousilahti, P

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关于体力活动与高血压风险相关的前瞻性研究很少,特别是在女性中。这项研究旨在找出有规律的体育锻炼是否可以降低男性和女性以及有超重和没有超重的受试者患高血压的风险。我们前瞻性地跟踪了8302名芬兰男性和9139名女性,年龄在25岁到之间,基线时没有抗高血压药物使用、冠心病、中风和心力衰竭的病史。使用COX比例风险模型检验了体力活动和体重指数与高血压风险的单一和联合关联。在平均11年的随访中,有1600例药物治疗高血压的病例。经多因素调整后,男性高血压与轻度、中度和高强度体力活动相关的危险比分别为1.00、0.63和0.59(P趋势
Prospective studies on physical activity in relation to the risk for hypertension are scant, particularly in women. This study aimed at finding out whether regular physical activity can reduce the risk of hypertension in both men and women, and in subjects with and without overweight. We prospectively followed 8302 Finnish men and 9139 women aged 25 to 64 years without a history of antihypertensive drug use, coronary heart disease, stroke, and heart failure at baseline. Both single and joint associations of physical activity and body mass index with the risk of hypertension were examined using Cox proportional hazard models. During a mean followup of 11 years, there were 1600 incident cases of drug-treated hypertension. Multivariate-adjusted hazards ratios of hypertension associated with light, moderate, and high physical activity were 1.00, 0.63, and 0.59 in men (P-trend